Allergen immunotherapy for allergic rhinoconjunctivitis: a systematic overview of systematic reviews.

ABSTRACT:

Background

The European Academy of Allergy and Clinical Immunology (EAACI) is developing Guidelines on Allergen Immunotherapy (AIT) for Allergic Rhinoconjunctivitis (ARC). To inform the development of recommendations, we sought to critically assess the systematic review evidence on the effectiveness, safety and cost-effectiveness of AIT for ARC.

Methods

We undertook a systematic overview, which involved searching nine international biomedical databases from inception to October 31, 2015. Studies were independently screened by two reviewers against pre-defined eligibility criteria and critically appraised using the Critical Appraisal Skills Programme (CASP) Systematic Review Checklist for systematic reviews. Data were descriptively synthesized.

Results

Our searches yie

SUBMITTER: Nurmatov U 

PROVIDER: S-EPMC5547534 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature