Nitric oxide is an obligate bacterial nitrification intermediate produced by hydroxylamine oxidoreductase.

ABSTRACT: Ammonia (NH₃)-oxidizing bacteria (AOB) emit substantial amounts of nitric oxide (NO) and nitrous oxide (N₂O), both of which contribute to the harmful environmental side effects of large-scale agriculture. The currently accepted model for AOB metabolism involves NH₃ oxidation to nitrite (NO₂^-) via a single obligate intermediate, hydroxylamine (NH₂OH). Within this model, the multiheme enzyme hydroxylamine oxidoreductase (HAO) catalyzes the four-electron oxidation of NH₂OH to NO₂^- We provide evidence that HAO oxidizes NH₂OH by only three electrons to NO under both anaerobic and aerobic conditions. NO₂^- observed in HAO activity assays is a nonenzymatic product res

SUBMITTER: Caranto JD 

PROVIDER: S-EPMC5547625 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature