Functional Decline is Associated with Hopelessness in Amyotrophic Lateral Sclerosis (ALS).

ABSTRACT:

Objective

To determine the relationships between hopelessness, depression, quality of life, and disease progression in ALS.

Methods

Hopelessness and depression were assessed prospectively in a cohort of people with ALS using the Beck Hopelessness scale (BHS) and the ALS Depression Inventory (ADI-12), respectively. ALS Specific Quality of Life and measures of functional status (ALSFRS-R and forced vital capacity) were collected. Associations between changes in psychological health and functional scores were calculated using Spearman correlation coefficients.

Results

Twenty-five people with ALS had at least 2 visits and were followed for a mean of 11 (± 6) months. People with hopelessness and depression reported worse quality of life (p<0.01 for both associations). Decl

SUBMITTER: Paganoni S 

PROVIDER: S-EPMC5548143 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature