Radiomic Features Are Associated With EGFR Mutation Status in Lung Adenocarcinomas.

ABSTRACT:

Background

In this study we retrospectively evaluated the capability of computed tomography (CT)-based radiomic features to predict epidermal growth factor receptor (EGFR) mutation status in surgically-resected peripheral lung adenocarcinomas in an Asian cohort of patients.

Patients and methods

Two hundred ninety-eight patients with surgically resected peripheral lung adenocarcinomas were investigated in this institutional review board-approved retrospective study with requirement waived to obtain informed consent. Two hundred nineteen quantitative 3-D features were extracted from segmented volumes of each tumor, and 59 of these, which were considered independent features, were included in the analysis. Clinical and pathological information was obtained from the institutiona

SUBMITTER: Liu Y 

PROVIDER: S-EPMC5548419 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature