Diffeomorphic functional brain surface alignment: Functional demons.

ABSTRACT: Aligning brain structures across individuals is a central prerequisite for comparative neuroimaging studies. Typically, registration approaches assume a strong association between the features used for alignment, such as macro-anatomy, and the variable observed, such as functional activation or connectivity. Here, we propose to use the structure of intrinsic resting state fMRI signal correlation patterns as a basis for alignment of the cortex in functional studies. Rather than assuming the spatial correspondence of functional structures between subjects, we have identified locations with similar connectivity profiles across subjects. We mapped functional connectivity relationships within the brain into an embedding space, and aligned the resulting maps of multiple subjects. We then perform

SUBMITTER: Nenning KH 

PROVIDER: S-EPMC5548603 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature