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Double impact: natural molluscicide for schistosomiasis vector control also impedes development of Schistosoma mansoni cercariae into adult parasites.


ABSTRACT:

Background

Schistosomiasis has been reported in 78 endemic countries and affects 240 million people worldwide. The digenetic parasite Schistosoma mansoni needs fresh water to compete its life cycle. There, it is susceptible to soluble compounds that can affect directly and/or indirectly the parasite's biology. The cercariae stage is one of the key points in which the parasite is vulnerable to different soluble compounds that can significantly alter the parasite's life cycle. Molluscicides are recommended by the World Health Organization for the control of schistosomiasis transmission and Euphorbia milii latex is effective against snails intermediate hosts.

Methodology/principal findings

We used parasitological tools and electron microscopy to verify the effects of cercariae

SUBMITTER: Augusto RC 

PROVIDER: S-EPMC5550001 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature