Residential Proximity to Roadways and Ischemic Placental Disease in a Cape Cod Family Health Study.

ABSTRACT: Exposure to air pollution may adversely impact placental function through a variety of mechanisms; however, epidemiologic studies have found mixed results. We examined the association between traffic exposure and placental-related obstetric conditions in a retrospective cohort study on Cape Cod, MA, USA. We assessed exposure to traffic using proximity metrics (distance of residence to major roadways and length of major roadways within a buffer around the residence). The outcomes included self-reported ischemic placental disease (the presence of at least one of the following conditions: preeclampsia, placental abruption, small-for-gestational-age), stillbirth, and vaginal bleeding. We used log-binomial regression models to estimate risk ratios (RR) and 95% confidence intervals (CI), adjusti

SUBMITTER: Wesselink AK 

PROVIDER: S-EPMC5551120 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature