Systemic Associations with Residual Subretinal Fluid after Ranibizumab in Diabetic Macular Edema.

ABSTRACT:

Purpose

To investigate the impact of systemic diseases on the occurrence of subretinal fluid (SRF) in diabetic macular edema (DME) and prognostic factors for residual SRF following three consecutive monthly intravitreal ranibizumab.

Methods

Ninety-seven eyes from 68 patients with DME who completed 3 consecutive monthly injections of ranibizumab were enrolled. Systemic parameters mainly included chronic kidney disease (CKD), hypertension, HbA1c, and insulin dependence. Renal parameters for CKD were serum creatinine, estimated glomerular filtration rate (eGFR), and serum albumin. Ocular factors were baseline central macular thickness (CMT), severity of diabetic retinopathy (DR), and status of panretinal photocoagulation (PRP).

Results

Chronic kidney disease had signific

SUBMITTER: Tsai MJ 

PROVIDER: S-EPMC5551529 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature