Management of Locally Recurrent Chordoma of the Mobile Spine and Sacrum: A Systematic Review.

ABSTRACT:

Study design

Systematic review.

Objective

To determine evidence-based guidelines for the management of locally recurrent spinal chordoma.

Summary of background data

Chordoma of the spine is a low-grade malignant tumor with a strong propensity for local recurrence. Salvage therapy is challenging due to its relentless nature and refractoriness to adjuvant therapies. There are currently no guidelines regarding the best management of recurrent chordoma.

Methods

We combined the results of a systematic review with expert opinion to address the following research questions: (1) For locally recurrent chordoma of the spine without systemic disease, if surgery is planned, should en bloc resection be attempted if technically feasible with acceptable morbidity? (2) For loc

SUBMITTER: Ailon T 

PROVIDER: S-EPMC5552168 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature