Correlation between p-STAT3 overexpression and prognosis in lung cancer: A systematic review and meta-analysis.

ABSTRACT:

Objective

Previous studies have shown the correlation between p-STAT3 overexpression and prognosis in a variety of human tumors. However, their correlation in lung cancer remains controversial. We performed a systematic review and meta-analysis to explore the correlation between p-STAT3 overexpression and prognosis in lung cancer patients.

Methods

We searched PubMed, Embase, Web of Science, CNKI, VIP, and WanFang Data to identify relevant studies. Two reviewers independently screened the literature search results, extracted data, and assessed the methodological quality of the included studies. Then, meta-analysis was performed by using Review Manager 5.3 and STATA 14 software. A random-effect model was employed to evaluate all related pooled results. Statistical heterogeneit

SUBMITTER: Tong M 

PROVIDER: S-EPMC5552221 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature