Reduced Cortical Thickness in the Temporal Pole, Insula, and Pars Triangularis in Patients with Panic Disorder.

ABSTRACT:

Purpose

Recent neuroimaging findings have revealed that paralimbic and prefrontal regions are involved in panic disorder (PD). However, no imaging studies have compared differences in cortical thickness between patients with PD and healthy control (HC) subjects.

Materials and methods

Forty-seven right-handed patients with PD who met the diagnostic criteria in the Diagnostic and Statistical Manual of Mental Disorders-4th edition-text revision, and 30 HC subjects were enrolled. We used the FreeSurfer software package for estimating the cortical thickness of regions of interest, including the temporal pole, insula, and pars triangularis (mid-ventrolateral prefrontal cortex).

Results

Cortical thickness of the temporal pole (p=0.033, right), insula (p=0.017, left), and par

SUBMITTER: Kang EK 

PROVIDER: S-EPMC5552629 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature