Polar Organizing Protein PopZ Is Required for Chromosome Segregation in Agrobacterium tumefaciens.

ABSTRACT: Despite being perceived as relatively simple organisms, many bacteria exhibit an impressive degree of subcellular organization. In Caulobacter crescentus, the evolutionarily conserved polar organizing protein PopZ facilitates cytoplasmic organization by recruiting chromosome centromeres and regulatory proteins to the cell poles. Here, we characterize the localization and function of PopZ in Agrobacterium tumefaciens, a genetically related species with distinct anatomy. In this species, we find that PopZ molecules are relocated from the old pole to the new pole in the minutes following cell division. PopZ is not required for the localization of the histidine kinases DivJ and PdhS1, which become localized to the old pole after PopZ relocation is complete. The histidine kinase PdhS2 is tempor

SUBMITTER: Ehrle HM 

PROVIDER: S-EPMC5553026 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature