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Swallowing markers in spinal and bulbar muscular atrophy.


ABSTRACT:

Objective

We examined the characteristics of dysphagia in spinal and bulbar muscular atrophy, a hereditary neuromuscular disease causing weakness of limb, facial, and oropharyngeal muscles via a videofluoroscopic swallowing study, and investigated the plausibility of using these outcome measures for quantitative analysis.

Methods

A videofluoroscopic swallowing study was performed on 111 consecutive patients with genetically confirmed spinal and bulbar muscular atrophy and 53 age- and sex-matched healthy controls. Swallowing of 3-mL liquid barium was analyzed by the Logemann's Videofluorographic Examination of Swallowing worksheet.

Results

Of more than 40 radiographic findings, the most pertinent abnormal findings in patients with spinal and bulbar muscular atro

SUBMITTER: Banno H 

PROVIDER: S-EPMC5553229 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature