Targeting Functional Decline in Alzheimer Disease: A Randomized Trial.

ABSTRACT:

Background

Alzheimer disease results in progressive functional decline, leading to loss of independence.

Objective

To determine whether collaborative care plus 2 years of home-based occupational therapy delays functional decline.

Design

Randomized, controlled clinical trial. (ClinicalTrials.gov: NCT01314950).

Setting

Urban public health system.

Patients

180 community-dwelling participants with Alzheimer disease and their informal caregivers.

Intervention

All participants received collaborative care for dementia. Patients in the intervention group also received in-home occupational therapy delivered in 24 sessions over 2 years.

Measurements

The primary outcome measure was the Alzheimer's Disease Cooperative Study Group Activities of Daily Li

SUBMITTER: Callahan CM 

PROVIDER: S-EPMC5554402 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature