RESOLUTE PET/MRI Attenuation Correction for O-(2-¹⁸F-fluoroethyl)-L-tyrosine (FET) in Brain Tumor Patients with Metal Implants.

ABSTRACT: Aim: Positron emission tomography (PET) imaging is a useful tool for assisting in correct differentiation of tumor progression from reactive changes, and the radiolabeled amino acid analog tracer O-(2-¹⁸F-fluoroethyl)-L-tyrosine (FET)-PET is amongst the most frequently used. The FET-PET images need to be quantitatively correct in order to be used clinically, which require accurate attenuation correction (AC) in PET/MRI. The aim of this study was to evaluate the use of the subject-specific MR-derived AC method RESOLUTE in post-operative brain tumor patients. Methods: We analyzed 51 post-operative brain tumor patients (68 examinations, 200 MBq [18F]-FET) investigated in a PET/MRI scanner. MR-AC maps were acquired using: (1) the Dixon water fat separation sequence, (2

SUBMITTER: Ladefoged CN 

PROVIDER: S-EPMC5554515 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature