Trichomonas vaginalis infection and risk of prostate cancer: associations by disease aggressiveness and race/ethnicity in the PLCO Trial.

ABSTRACT:

Purpose

Results from previous sero-epidemiologic studies of Trichomonas vaginalis infection and prostate cancer (PCa) support a positive association between this sexually transmitted infection and aggressive PCa. However, findings from previous studies are not entirely consistent, and only one has investigated the possible relation between T. vaginalis seropositivity and PCa in African-American men who are at highest risk of both infection and PCa. Therefore, we examined this possible relation in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial, including separate analyses for aggressive PCa and African-American men.

Methods

We included a sample of participants from a previous nested case-control study of PCa, as well as all additional Caucasian, aggressive

SUBMITTER: Marous M 

PROVIDER: S-EPMC5554601 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature