Brain grey and white matter predictors of verbal ability traits in older age: The Lothian Birth Cohort 1936.

ABSTRACT: Cerebral grey and white matter MRI parameters are related to general intelligence and some specific cognitive abilities. Less is known about how structural brain measures relate specifically to verbal processing abilities. We used multi-modal structural MRI to investigate the grey matter (GM) and white matter (WM) correlates of verbal ability in 556 healthy older adults (mean age = 72.68 years, s.d. = .72 years). Structural equation modelling was used to decompose verbal performance into two latent factors: a storage factor that indexed participants' ability to store representations of verbal knowledge and an executive factor that measured their ability to regulate their access to this information in a flexible and task-appropriate manner. GM volumes and WM fractional anisotropy (FA) for c

SUBMITTER: Hoffman P 

PROVIDER: S-EPMC5554782 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature