Multi-modal neuroimaging of adolescents with non-suicidal self-injury: Amygdala functional connectivity.

ABSTRACT:

Background

Non-suicidal self-injury (NSSI) is a significant mental health problem among adolescents. Research is needed to clarify the neurobiology of NSSI and identify candidate neurobiological targets for interventions. Based on prior research implicating heightened negative affect and amygdala hyperactivity in NSSI, we pursued a systems approach to characterize amygdala functional connectivity networks during rest (resting-state functional connectivity [RSFC)]) and a task (task functional connectivity [TFC]) in adolescents with NSSI.

Method

We examined amygdala networks in female adolescents with NSSI and healthy controls (n = 45) using resting-state fMRI and a negative emotion face-matching fMRI task designed to activate the amygdala. Connectivity analyses included amygd

SUBMITTER: Westlund Schreiner M 

PROVIDER: S-EPMC5555154 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature