Electrophoretic Separation of Single Particles Using Nanoscale Thermoplastic Columns.

ABSTRACT: Phenomena associated with microscale electrophoresis separations cannot, in many cases, be applied to the nanoscale. Thus, understanding the electrophoretic characteristics associated with the nanoscale will help formulate relevant strategies that can optimize the performance of separations carried out on columns with at least one dimension below 150 nm. Electric double layer (EDL) overlap, diffusion, and adsorption/desorption properties and/or dielectrophoretic effects giving rise to stick/slip motion are some of the processes that can play a role in determining the efficiency of nanoscale electrophoretic separations. We investigated the performance characteristics of electrophoretic separations carried out in nanoslits fabricated in poly(methyl methacrylate), PMMA, devices. Silver nanopa

SUBMITTER: Weerakoon-Ratnayake KM 

PROVIDER: S-EPMC5555359 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature