TaiNi: Maximizing research output whilst improving animals' welfare in neurophysiology experiments.

ABSTRACT: Understanding brain function at the cell and circuit level requires representation of neuronal activity through multiple recording sites and at high sampling rates. Traditional tethered recording systems restrict movement and limit the environments suitable for testing, while existing wireless technology is still too heavy for extended recording in mice. Here we tested TaiNi, a novel ultra-lightweight (<2 g) low power wireless system allowing 72-hours of recording from 16 channels sampled at ~19.5 KHz (9.7 KHz bandwidth). We captured local field potentials and action-potentials while mice engaged in unrestricted behaviour in a variety of environments and while performing tasks. Data was synchronized to behaviour with sub-second precision. Comparisons with a state-of-the-art wireless system

SUBMITTER: Jiang Z 

PROVIDER: S-EPMC5556067 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature