The global burden of tuberculosis mortality in children: a mathematical modelling study.

ABSTRACT:

Background

Tuberculosis in children is increasingly recognised as an important component of the global tuberculosis burden, with an estimated 1 million cases in 2015. Although younger children are vulnerable to severe forms of tuberculosis disease, no age-disaggregated estimates of paediatric tuberculosis mortality exist, and tuberculosis has never been included in official estimates of under-5 child mortality. We aimed to produce a global mortality burden estimate in children using a complementary approach not dependent on vital registration data.

Methods

In this mathematical modelling study, we estimated deaths in children younger than 5 years and those aged 5-14 years for 217 countries and territories using a case-fatality-based approach. We used paediatric tuberculosis n

SUBMITTER: Dodd PJ 

PROVIDER: S-EPMC5556253 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature