Inflammation and pro-resolution inflammation after hepatobiliary surgery.

ABSTRACT:

Background

The magnitude of the perioperative inflammatory response plays a role in surgical outcomes. However, few studies have explored the mechanisms of the resolution of inflammation in the context of surgery. Here, we described the temporal kinetics of interleukin-6, cortisol, lipoxin A4, and resolvin D in patients who underwent oncologic liver resections.

Methods

All patients gave written informed consent. Demographic and perioperative surgical data were collected, along with blood samples, before surgery and on the mornings of postoperative days 1, 3, and 5. Interleukin-6, cortisol, lipoxin-A4, and resolvin D were measured in plasma. A P value < 0.05 was considered statistically significant.

Results

Forty-one patients were included in the study. Liver resection

SUBMITTER: Cata JP 

PROVIDER: S-EPMC5556621 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature