A Swedish approach to the prevention of type 1 diabetes.

ABSTRACT:

Background

The autoimmune destruction of beta cells, resulting in clinical type 1 diabetes, may start early in life and last for several months or years. During this period of time, we have an opportunity to try to prevent or delay further beta-cell destruction and clinical onset of type 1 diabetes.

Objectives

Ongoing prediction and prevention studies in Skåne, Sweden are described.

Methods

During September 2000 to August 2004, 35 000 children were screened at birth for genetic type 1 diabetes risk in the Diabetes Prediction in Skåne Study (DiPiS). In August 2004, the screening continued within the Enviromnental Determinants of Diabetes in the Young study (TEDDY). In the clinical trial Diabetes Prevention - Immune Tolerance (DiAPREV-IT), children with multiple islet a

SUBMITTER: Elding Larsson H 

PROVIDER: S-EPMC5556697 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature