Therapeutic Strategies Targeting Inherited Cardiomyopathies.

ABSTRACT:

Purpose of review

Cardiomyopathies due to genetic mutations are a heterogeneous group of disorders that comprise diseases of contractility, myocardial relaxation, and arrhythmias. Our goal here is to discuss a limited list of genetically inherited cardiomyopathies and the specific therapeutic strategies used to treat them.

Recent findings

Research into the molecular pathophysiology of the development of these cardiomyopathies is leading to the development of novel treatment approaches. Therapies targeting these specific mutations with gene therapy vectors are on the horizon, while other therapies which indirectly affect the physiologic derangements of the mutations are currently being studied and used clinically. Many of these therapies are older medications being given new

SUBMITTER: Varian K 

PROVIDER: S-EPMC5557031 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature