Sponsorship bias and quality of randomised controlled trials in veterinary medicine.

ABSTRACT:

Background

Randomised controlled trials (RCTs) are considered the gold standard form of evidence for assessing treatment efficacy, but many factors can influence their reliability including methodological quality, reporting quality and funding source. The aim of this study was to examine the relationship between funding source and positive outcome reporting in veterinary RCTs published in 2011 and to assess the risk of bias in the RCTs identified.

Methods

A structured search of PubMed was used to identify feline, canine, equine, bovine and ovine clinical trials examining the efficacy of pharmaceutical interventions published in 2011. Funding source and outcomes were extracted from each RCT and an assessment of risk of bias made using the Cochrane risk of bias tool.

Result

SUBMITTER: Wareham KJ 

PROVIDER: S-EPMC5557072 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature