Ontology highlight
ABSTRACT:
SUBMITTER: McClure EE
PROVIDER: S-EPMC5557331 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Nature reviews. Microbiology 20170619 9
It is estimated that approximately one billion people are at risk of infection with obligate intracellular bacteria, but little is known about the underlying mechanisms that govern their life cycles. The difficulty in studying Chlamydia spp., Coxiella spp., Rickettsia spp., Anaplasma spp., Ehrlichia spp. and Orientia spp. is, in part, due to their genetic intractability. Recently, genetic tools have been developed; however, optimizing the genomic manipulation of obligate intracellular bacteria r ...[more]