Genomic data illuminates demography, genetic structure and selection of a popular dog breed.

ABSTRACT:

Background

Genomic methods have proved to be important tools in the analysis of genetic diversity across the range of species and can be used to reveal processes underlying both short- and long-term evolutionary change. This study applied genomic methods to investigate population structure and inbreeding in a common UK dog breed, the Labrador Retriever.

Results

We found substantial within-breed genetic differentiation, which was associated with the role of the dog (i.e. working, pet, show) and also with coat colour (i.e. black, yellow, brown). There was little evidence of geographical differentiation. Highly differentiated genomic regions contained genes and markers associated with skull shape, suggesting that at least some of the differentiation is related to human-imposed

SUBMITTER: Wiener P 

PROVIDER: S-EPMC5557481 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature