Resting state hypothalamic response to glucose predicts glucose-induced attenuation in the ventral striatal response to food cues.

ABSTRACT: Feeding behavior is regulated by a complex interaction of central nervous system responses to metabolic signals that reflect nutrient availability and to food cues that trigger appetitive responses. Prior work has shown that the hypothalamus is a key brain area that senses and responds to changes in metabolic signals, and exposure to food cues induces the activation of brain areas involved in reward processing. However, it is not known how the hypothalamic responses to changes in metabolic state are related to reward responses to food cues. This study aimed to understand whether changes in hypothalamic activity in response to glucose-induced metabolic signals are linked to food-cue reactivity within brain areas involved in reward processing. We combined two neuroimaging modalities (Arteria

SUBMITTER: Luo S 

PROVIDER: S-EPMC5557629 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature