Association of ectopic fat with abdominal aorto-illiac and coronary artery calcification in african ancestry men.

ABSTRACT:

Background and aims

There is strong evidence that fat accumulating in non-adipose sites, "ectopic fat", is associated with cardiovascular disease (CVD), including vascular calcification. Most previous studies of this association have assessed only a single ectopic fat depot. Therefore, our aim was to assess the association of total, regional, and ectopic fat with abdominal aorto-illiac calcification (AAC) and coronary artery calcification (CAC) in 798 African ancestry men.

Methods

Participants (mean age 62) were from the Tobago Bone Health Study cohort. Adiposity was assessed via clinical examination, dual x-ray absorptiometry, and computed tomography (CT). Ectopic fat depots included: abdominal visceral adipose tissue (VAT), liver attenuation, and calf intermuscular adipose

SUBMITTER: Kuipers AL 

PROVIDER: S-EPMC5557679 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature