A Novel Method to Detect 3D Mandibular Changes Related to Soft-Diet Feeding.

ABSTRACT: Craniofacial morphology varies among individuals, which is regulated by the interaction between genes and the environment. Soft-diet feeding is a widely-used experimental model for studying the association between the skeletal morphology and muscle-related loading on the bone. Traditionally, these studies have been based on linear and angular measurements provided on two-dimensional (2D) radiographs in the lateral view. However, 2D observation is based on simplification of the anatomical structures and cannot detect three-dimensional (3D) changes in detail. In this study, we newly developed a modified surface-based analysis with micro-3D computed tomography (CT) to examine and detect the 3D changes in the mandible associated with soft-diet feeding. Mice at 3 weeks of age were fed a powdere

SUBMITTER: Kono K 

PROVIDER: S-EPMC5557733 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature