Fertility Treatment and Childhood Epilepsy: A Nationwide Cohort Study.

ABSTRACT:

Background

Fertility treatment includes hormonal stimulation of the woman and in vitro manipulation of gametes and embryos that may influence prenatal brain development. We aimed to investigate the association between fertility treatment and childhood epilepsy, including specific types of treatment and indications, as well as subtypes of epilepsy.

Methods

In this nationwide birth cohort study, we included all pregnancies in Denmark resulting in live-born singletons, 1995-2003. Children conceived by fertility treatment and children developing epilepsy (until 2013) were identified from Danish national registers.

Results

A total of 565,116 pregnancies were included; 8,071 children (1.4%) developed epilepsy. Children conceived after ovulation induction or intrauterine ins

SUBMITTER: Kettner LO 

PROVIDER: S-EPMC5558039 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature