Ontology highlight
ABSTRACT: Background
Smoking influences body weight, but there is little evidence as to whether body mass index (BMI) and body dissatisfaction increase smoking initiation in adolescents.Methods
We evaluated the association between measured BMI, body dissatisfaction and latent classes of smoking initiation (never smokers, experimenters, late onset regular smokers, early onset regular smokers) in the Avon Longitudinal Study of Parents and Children. In observational analyses we used BMI (N=3754) and body dissatisfaction at age 10.5 years (N=3349). In Mendelian randomisation (MR) analysis, we used a BMI genetic risk score of 76 single nucleotide polymorphisms (N=4017).Results
In females, higher BMI was associated with increased odds of early onset regular smoking (OR: 1.11, 95% C
SUBMITTER: Howe LJ
PROVIDER: S-EPMC5558147 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature