Ontology highlight
ABSTRACT:
SUBMITTER: Ramachandran G
PROVIDER: S-EPMC5559095 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Ramachandran Girish G Panda Aruna A Higginson Ellen E EE Ateh Eugene E Lipsky Michael M MM Sen Sunil S Matson Courtney A CA Permala-Booth Jasnehta J DeTolla Louis J LJ Tennant Sharon M SM
PLoS neglected tropical diseases 20170804 8
Salmonella Typhimurium sequence type (ST) 313 produces septicemia in infants in sub-Saharan Africa. Although there are known genetic and phenotypic differences between ST313 strains and gastroenteritis-associated ST19 strains, conflicting data about the in vivo virulence of ST313 strains have been reported. To resolve these differences, we tested clinical Salmonella Typhimurium ST313 and ST19 strains in murine and rhesus macaque infection models. The 50% lethal dose (LD50) was determined for thr ...[more]