Developmental effects of fipronil on Japanese Medaka (Oryzias latipes) embryos.

ABSTRACT: Pesticides in urban runoff are a major source of pollutants in aquatic ecosystems. Fipronil, a phenylpyrazole insecticide, found in structural pest control products, turf grass control, and home pet flea medication, has recently increased in use and is commonly detected in urban runoff. However, little is known about the effects of fipronil on aquatic organisms at early developmental stages. Here, we evaluated toxicity of fipronil to embryos of Japanese Medaka (Oryzias latipes, Qurt strain) using a high-throughput 96-well plate toxicity test. Male and female embryos (<6 h post fertilization) were exposed to concentrations of fipronil ranging from 0.1 to 910 μg L^-1 for 14 days or until hatching. Embryos were subjected to gross and microscopic examinations of developmental adverse

SUBMITTER: Wagner SD 

PROVIDER: S-EPMC5560107 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature