Glycocalyx scaffolding with synthetic nanoscale glycomaterials.

ABSTRACT: We report a method for programming complexity into the glycocalyx of live cells. Via a combination of glycomaterial synthesis and membrane remodeling, we have engineered cells to display native-like, mixed sialoglycan populations, while confining the activity of each glycan into a specific nanoscale presentation.

SUBMITTER: Huang ML 

PROVIDER: S-EPMC5560263 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature