Lingual microbiota profiles of patients with geographic tongue.

ABSTRACT: Geographic tongue (GT) is an oral mucosal lesion that affects the tongue. The association between GT and the bacterial colonization profiles of the tongue is not clear. Lingual swabs were collected from lesion sites and healthy sites of 35 patients with GT (19 males and 16 females; M_age = 54.3 ± 16.1 years) and 22 controls (12 males and 10 females; M_age = 56.3 ± 15.8 years). Bacterial DNA was extracted and sequenced by next-generation sequencing. At the phylum level, Fusobacteria were significantly less abundant, while Spirochaetes were significantly more abundant in GT patients compared to controls. At the operational taxonomic units level, multivariate analysis revealed distinct clusters for the three groups based on the lingual microbiota composition. Acinetobacter

SUBMITTER: Dafar A 

PROVIDER: S-EPMC5560410 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature