Association Between ABCB1 Gene Polymorphism and Renal Function in Patients with Hypertension: A Case-Control Study.

ABSTRACT: BACKGROUND A previous study found that target organ damage in patients with hypertension was related to genetic factors. The aim of our study aim was to explore the association between the ABCB1 gene and renal function injury induced by hypertension. MATERIAL AND METHODS We used a case-control study design. Patients with hypertension were enrolled from our hospital between July 2015 and December 2015. Questionnaire data included personal information, life habits and behavior. Clinical data included blood routine examination and liver and renal function. We used restriction fragment length polymorphism methods for ABCB1 gene polymorphism detection. RESULTS There were 306 patients with hypertension included in the final analyses: 170 cases of hypertension and 136 controls. Compared to contro

SUBMITTER: Chen X 

PROVIDER: S-EPMC5560471 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature