Majority of human traits do not show evidence for sex-specific genetic and environmental effects.

ABSTRACT: Sex differences in the etiology of human trait variation are a major topic of interest in the social and medical sciences given its far-reaching implications. For example, in genetic research, the presence of sex-specific effects would require sex-stratified analysis, and in clinical practice sex-specific treatments would be warranted. Here, we present a study of 2,335,920 twin pairs, in which we tested sex differences in genetic and environmental contributions to variation in 2,608 reported human traits, clustered in 50 trait categories. Monozygotic and dizygotic male and female twin correlations were used to test whether the amount of genetic and environmental influences was equal between the sexes. By comparing dizygotic opposite sex twin correlations with dizygotic same sex twin correl

SUBMITTER: Stringer S 

PROVIDER: S-EPMC5561094 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature