Intradialytic Central Venous Oxygen Saturation is Associated with Clinical Outcomes in Hemodialysis Patients.

ABSTRACT: Central venous oxygen saturation (ScvO₂) in the superior vena cava is predominantly determined by cardiac output, arterial oxygen content, and oxygen consumption by the upper body. While abnormal ScvO₂ levels are associated with morbidity and mortality in non-uremic populations, ScvO₂ has received little attention in hemodialysis patients. From 1/2012 to 8/2015, 232 chronic hemodialysis patients with central venous catheters as vascular access had their ScvO₂ monitored during a 6-month baseline period and followed for up to 36 months. Patients were stratified into upper and lower two tertiles by a ScvO₂ of 61.1%. Survival analysis employed Kaplan-Meier curves and adjusted Cox proportional hazards models. Patients in the lower tertiles

SUBMITTER: Chan L 

PROVIDER: S-EPMC5561134 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature