Staphylococcus aureus Strain Newman Photoinactivation and Cellular Response to Sunlight Exposure.

ABSTRACT: Sunlight influences microbial water quality of surface waters. Previous studies have investigated photoinactivation mechanisms and cellular photostress responses of fecal indicator bacteria (FIB), including Escherichia coli and enterococci, but further work is needed to characterize photostress responses of bacterial pathogens. Here we investigate the photoinactivation of Staphylococcus aureus (strain Newman), a pigmented, waterborne pathogen of emerging concern. We measured photodecay using standard culture-based assays and cellular membrane integrity and investigated photostress response by measuring the relative number of mRNA transcripts of select oxidative stress, DNA repair, and metabolism genes. Photoinactivation experiments were performed in both oxic and anoxic syste

SUBMITTER: McClary JS 

PROVIDER: S-EPMC5561283 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature