Peripubertal blood lead levels and growth among Russian boys.

ABSTRACT:

Background

Childhood blood lead levels (BLL) have been associated with growth impairment.

Objectives

We assessed associations of peripubertal BLL with adolescent growth and near adult height in a longitudinal cohort of Russian boys.

Methods

481 boys were enrolled at ages 8-9years and followed annually to age 18. At enrollment, BLL was measured, and height, weight, and pubertal staging were obtained annually during 10years of follow-up. Mixed effects models were used to assess the associations of BLL with longitudinal age-adjusted World Health OrganizationZ-scores for height (HT-Z) and body mass index (BMI-Z), and annual height velocity (HV). Interactions between boys' age and BLL on growth outcomes were evaluated.

Results

The median (range) BLL was 3.0 (0.5-31.

SUBMITTER: Burns JS 

PROVIDER: S-EPMC5561550 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature