Combined gadoxetic acid and gadofosveset enhanced liver MRI for detection and characterization of liver metastases.

ABSTRACT:

Purpose

To compare gadoxetic acid alone and combined gadoxetic acid/gadofosveset trisodium-enhanced liver MRI for detection of metastases and differentiation of metastases from haemangiomas.

Methods

Ninety-one patients underwent gadoxetic acid-enhanced liver MRI before and after additional injection of gadofosveset. First, two readers retrospectively identified metastases on gadoxetic acid alone enhanced delayed hepatobiliary phase T1-weighted images together with all other MR images (dynamic images, T2-weighted images, diffusion-weighted images). Second, readers assessed additional T1-weighted images obtained after administration of gadofosveset trisodium. For both interpretations, readers rated lesion conspicuity and confidence in differentiating metastases from haemangiom

SUBMITTER: Bannas P 

PROVIDER: S-EPMC5562159 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature