Altered fetal growth, placental abnormalities, and stillbirth.

ABSTRACT:

Background

Worldwide, stillbirth is one of the leading causes of death. Altered fetal growth and placental abnormalities are the strongest and most prevalent known risk factors for stillbirth. The aim of this study was to identify patterns of association between placental abnormalities, fetal growth, and stillbirth.

Methods and findings

Population-based case-control study of all stillbirths and a representative sample of live births in 59 hospitals in 5 geographic areas in the U.S. Fetal growth abnormalities were categorized as small (<10th percentile) and large (>90th percentile) for gestational age at death (stillbirth) or delivery (live birth) using a published algorithm. Placental examination by perinatal pathologists was performed using a standardized protocol. Data wer

SUBMITTER: Bukowski R 

PROVIDER: S-EPMC5562325 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature