Co-Registration of ex vivo Surgical Histopathology and in vivo T2 weighted MRI of the Prostate via multi-scale spectral embedding representation.

ABSTRACT: Multi-modal image co-registration via optimizing mutual information (MI) is based on the assumption that intensity distributions of multi-modal images follow a consistent relationship. However, images with a substantial difference in appearance violate this assumption, thus MI directly based on image intensity alone may be inadequate to drive similarity based co-registration. To address this issue, we introduce a novel approach for multi-modal co-registration called Multi-scale Spectral Embedding Registration (MSERg). MSERg involves the construction of multi-scale spectral embedding (SE) representations from multimodal images via texture feature extraction, scale selection, independent component analysis (ICA) and SE to create orthogonal representations that decrease the dissimilarity betw

SUBMITTER: Li L 

PROVIDER: S-EPMC5562695 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature