Transcriptome analysis reveals long intergenic non-coding RNAs involved in skeletal muscle growth and development in pig.

ABSTRACT: Long intergenic non-coding RNAs (lincRNAs) play essential roles in numerous biological processes and are widely studied. The skeletal muscle is an important tissue that plays an essential role in individual movement ability. However, lincRNAs in pig skeletal muscles are largely undiscovered and their biological functions remain elusive. In this study, we assembled transcriptomes using RNA-seq data published in previous studies of our laboratory group and identified 323 lincRNAs in porcine leg muscle. We found that these lincRNAs have shorter transcript length, fewer exons and lower expression level than protein-coding genes. Gene ontology and pathway analyses indicated that many potential target genes (PTGs) of lincRNAs were involved in skeletal-muscle-related processes, such as muscle con

SUBMITTER: Zou C 

PROVIDER: S-EPMC5562803 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature