Ambient ultraviolet radiation exposure and hepatocellular carcinoma incidence in the United States.

ABSTRACT:

Background

Hepatocellular carcinoma (HCC), the most commonly occurring type of primary liver cancer, has been increasing in incidence worldwide. Vitamin D, acquired from sunlight exposure, diet, and dietary supplements, has been hypothesized to impact hepatocarcinogenesis. However, previous epidemiologic studies examining the associations between dietary and serum vitamin D reported mixed results. The purpose of this study was to examine the association between ambient ultraviolet (UV) radiation exposure and HCC risk in the U.S.

Methods

The Surveillance, Epidemiology, and End Results (SEER) database provided information on HCC cases diagnosed between 2000 and 2014 from 16 population-based cancer registries across the U.S. Ambient UV exposure was estimated by linking the SEER

SUBMITTER: VoPham T 

PROVIDER: S-EPMC5562984 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature