Facial Curvature Detects and Explicates Ethnic Differences in Effects of Prenatal Alcohol Exposure.

ABSTRACT:

Background

Our objective is to help clinicians detect the facial effects of prenatal alcohol exposure by developing computer-based tools for screening facial form.

Methods

All 415 individuals considered were evaluated by expert dysmorphologists and categorized as (i) healthy control (HC), (ii) fetal alcohol syndrome (FAS), or (iii) heavily prenatally alcohol exposed (HE) but not clinically diagnosable as FAS; 3D facial photographs were used to build models of facial form to support discrimination studies. Surface curvature-based delineations of facial form were introduced.

Results

(i) Facial growth in FAS, HE, and control subgroups is similar in both cohorts. (ii) Cohort consistency of agreement between clinical diagnosis and HC-FAS facial form classification is lower

SUBMITTER: Suttie M 

PROVIDER: S-EPMC5563255 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature