Paternal and maternal urinary phthalate metabolite concentrations and birth weight of singletons conceived by subfertile couples.

ABSTRACT:

Background

Prenatal phthalate exposure has been inconsistently associated with fetal growth and infant birth weight. However, the effect of exposure during the paternal and maternal preconception period remains understudied.

Objectives

To investigate associations of paternal and maternal preconception and maternal prenatal urinary phthalate metabolite concentrations with birth weight.

Methods

The study comprised 364 singletons born to 364 mothers and 195 fathers (195 couples) from the EARTH Study, a prospective cohort of couples from Boston, MA. Births were categorized by mode of conception: in-vitro fertilization based (IVF) (n=208) or non-IVF based (n=156, intrauterine insemination or non-medically assisted/natural conception). We measured urinary concentrations of

SUBMITTER: Messerlian C 

PROVIDER: S-EPMC5563279 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature