Results of Screening in Familial Non-Medullary Thyroid Cancer.

ABSTRACT:

Background

Although a family history of thyroid cancer is one of the main risk factors for thyroid cancer, the benefit of screening individuals with a family history of thyroid cancer is not known.

Methods

A prospective cohort study was performed with yearly screening using neck ultrasound and fine-needle aspiration biopsy of thyroid nodule(s) >0.5 cm in at-risk individuals whose relatives were diagnosed with familial non-medullary thyroid cancer (FNMTC). The eligibility criteria were the presence of thyroid cancer in two or more first-degree relatives and being older than seven years of age. Twenty-five kindred were enrolled in the study (12 families with two members affected, and 13 with three or more members affected at enrollment).

Results

Thyroid cancer was detec

SUBMITTER: Klubo-Gwiezdzinska J 

PROVIDER: S-EPMC5564020 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature