Cancer killers in the human gut microbiota: diverse phylogeny and broad spectra.

ABSTRACT: Cancer as a large group of complex diseases is believed to result from the interactions of numerous genetic and environmental factors but may develop in people without any known genetic or environmental risks, suggesting the existence of other powerful factors to influence the carcinogenesis process. Much attention has been focused recently on particular members of the intestinal microbiota for their potential roles in promoting carcinogenesis. Here we report the identification and characterization of intestinal bacteria that exhibited potent anti-malignancy activities on a broad range of solid cancers and leukemia. We collected fecal specimens from healthy individuals of different age groups (preschool children and university students), inspected their effects on cancer cells, and obtaine

SUBMITTER: Zhou YJ 

PROVIDER: S-EPMC5564789 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature